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Author ORCID Identifier

Tareq Maqlam : ORCID: 0009-0007-4272-4620

Abdullah H Maad : ORCID: 0000-0002-6009-5166

Abstract

Ciprofloxacin is one of the most common antibacterial drugs used mainly for gastrointestinal and urinary tract infections. This study aimed to compare the quality specifications of two Yemeni ciprofloxacin hydrochloride tablet products with two non-Yemeni brands. Samples were randomly selected from different batch numbers and subjected to physicochemical testing in accordance with pharmacopeial monographs. Additionally, microbiological susceptibility testing was performed against Staphylococcus aureus and Escherichia coli. All tested products complied with pharmacopoeial standards for weight uniformity (Escherichia coli and Staphylococcus aureus, with brand D demonstrating the highest activity. These findings suggest that Yemeni ciprofloxacin tablets meet quality standards comparable to non-Yemeni products, supporting their potential as effective alternatives.

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