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Abstract

IntroductionThis study aimed to examine the association between breastfeeding practices and the risk reduction of childhood leukemia, and to identify the optimal breastfeeding duration for infant health. A case-control design was used, involving children aged 0–16 years diagnosed with leukemia and a matched control group without leukemia.MethodsData were collected on breastfeeding duration, type of feeding during the first six months, maternal characteristics (age, education, smoking during pregnancy, abortion history, birth control pill use), and child-related variables (sex, age at diagnosis, and birth order). Statistical analysis was conducted using SPSS Version 27. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated, and a p-value of12 months) was more frequent in controls (32%) than in cases (16%). Lower maternal education was significantly associated with leukemia cases (p = 0.001). Logistic regression showed exclusive breastfeeding (OR = 0.501, p < 0.001) and breastfeeding >12 months (OR = 0.721, p = 0.001) were protective.ConclusionExclusive and prolonged breastfeeding significantly reduce the risk of childhood leukemia. Maternal education is also an important factor, underscoring the need for public health initiatives to promote breastfeeding awareness

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