Abstract
Background: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting reproductive-aged women. It has been associated with metabolic disturbances that may increase the risk of hypertension. Objective: This study aimed to evaluate the association between PCOS and hypertension, with a particular focus on anti-Müllerian hormone (AMH) as a potential biomarker. Methods: A case-control involving women aged 15-45 years (mean of age 28.666±6.837) years, divided into two groups n=45 (mean of age 31.689 ± 6.842) used as controls and n=45 patients (mean of age 24.644 ± 5.390), The serum LH, FSH, insulin, prolactin, and testosterone were measured using ELISA. Result: A significant increase (p≤0.01) was observed in diastolic pressure in PCOS patients (8.04±0.82) compared to the control group (7.40±0.54), No significant difference was observed in systolic blood pressure on hormonal parameters found elevated in AMH in patient (2386.14±530.09) compared to control (895.01±198.18), prolactin, testosterone, and LH, and a significant decrease observed in FSH. Conclusion: Obesity, low-grade inflammation, and hyperinsulinemia are prevalent in PCOS, which leads to an increase in hypertension that makes women with PCOS more likely to develop hypertension and cardiovascular complications.
Recommended Citation
Khaleel, Ayat Salim; Al-Fatlawi, Abeer Gheaid Yousif; and Al-Safee, Wasan Ghazi Aboud
(2025)
"Evaluation of the relationship between polycystic ovarian syndrome and hypertension: A case-control study,"
Al-Ameed Journal for Medical Research and Health Sciences: Vol. 3
:
Iss.
2
, Article 3.
Available at:
https://doi.org/10.61631/3005-3188.1028